Caine is disposed of by means of chemical waste, but the chemicals do not kill him instead, they alter him into the angry, sentient, formless creature known as 'The Ooze'. However, the Director of The Corporation discovers Caine in the lab. Caine discovers that his colleagues are planning 'Operation: Omega': a plan to release a plague upon the populace, and make a fortune because they hold the only cure. Daniel Caine sneaking into the research lab where he worked, in order to find evidence that crimes were being committed using a toxic gas he created. This game is part of a large collection of Mega Drive games in The Strong's collection that represent nearly 100% of all games released for that system.The game starts at a chemical plant known as 'The Corporation,' with scientist Dr. Mega Drive games also received re-release as part of collector's editions for the Sony PS2 and PSP, and other systems, as well as being available for download on the Nintendo Wii Virtual Console. Games continued to be released internationally as recently as 2002.

The first successful 16-bit system, the Mega Drive's 14-year lifespan places it second only to the Nintendo Game Boy. With seven distinct versions, it also has the largest number of licensed versions of any console. The Mega Drive/Genesis also supported a number of add-on components (32X, CD, Power Base Converter), making it one of the most flexible systems ever developed. The Genesis could do things that the NES simply couldn't. Sega also focused attention on its better graphics, speed, and sound, especially after the release of Sonic. These efforts were often successful, as Sega marketed the Genesis as hip, cool, and edgy. In addition to porting over popular coin-op games, Sega executives worked hard to lure developers away from Nintendo. Dubbed the Genesis, this version was developed with the American market and consumer in mind. A year later, Sega released the Mega Drive in the United States.

Released in 1988, the Sega Mega Drive heralded the coming of the 16-bit era and inaugurated the Console Wars of the 1990s.

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